Stem Cell News You Can Use (111606)
That’s means it’s from stem cells of the “adult” variety, of course:
Stem cell cure hope for diabetes
Published: 2006/11/12 00:20:17 GMTScientists have used stem cells from human bone marrow to repair defective insulin-producing pancreatic cells responsible for diabetes in mice.
The treatment also halted damage to the kidneys caused by the condition.
Researchers from New Orleans’ Tulane University are hopeful it can be adapted to treat diabetes in humans.
Stem cells are immature cells which have the capacity to turn into any kind of tissue in the body.The US team treated diabetic mice who had high blood sugar and damaged kidneys.
One group of mice were injected with stem cells. After three weeks they were shown to be producing higher levels of mouse insulin than untreated mice and had lower blood sugar levels.
The injections also appeared to halt damaging changes taking place in the glomeruli, the bulb-like structures in the kidneys that filter the blood.
Researcher Dr Darwin Prockop said: “We are not certain whether the kidneys improved because the blood sugar was lower or because the human cells were helping to repair the kidneys.
“But we suspect the human cells were repairing the kidneys in much the same way they were repairing the insulin-producing cells in the pancreas.”
Growing problem
Dr Prockop said his team were planning to carry out trials in patients with diabetes.
“The physicians will be selecting patients with diabetes whose kidneys are beginning to fail.









